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UroLongevity: What Comprehensive Longevity Medicine Offers

The full account — 49 chapters across seven parts. The frameworks, the evidence, and the honest limitations behind this way of practicing medicine.

The pitch

The deep version of everything this practice believes.

This website introduces comprehensive longevity medicine. The book is where the subject is treated in full — carefully, and at length.

It is written for the serious reader: someone who wants to understand the biology of aging, the major intervention classes, the state of the evidence, and the honest limits of what this medicine can do. It is not a marketing document and not a protocol manual. It is the reasoning, laid out completely.

Across 49 chapters it moves from foundations — how to read medical evidence, the biology of aging — through the metabolic, molecular, and hormonal systems, and closes with how an integrated practice actually works.

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UroLongevity
What Comprehensive Longevity Medicine Offers
David Shusterman, MD
49 chapters · 7 parts
The full structure

Table of contents

Part I — Foundations

  1. The Body Speaks in Signals
  2. Not a Steroid, Not a Supplement, Not Snake Oil
  3. The Longevity Marketplace
  4. How to Read Medical Evidence
  5. The Biology of Aging
  6. The Metabolic Engine
  7. Energy, Mitochondria, and Fatigue

Part II — The Metabolic Frontier

  1. The GLP-1 Revolution
  2. The Peptide Landscape
  3. Growth and Repair Signals
  4. Sexual Health and Vascular Function
  5. Tissue, Healing, and Recovery
  6. The Gut as a Metabolic Organ
  7. Inflammation as a Through-Line

Part III — Molecular Longevity

  1. NAD+ and Cellular Energy
  2. Senescence and the Aging Cell
  3. Autophagy and Cellular Housekeeping
  4. mTOR, Rapamycin, and Nutrient Sensing
  5. Mitochondrial Medicine
  6. Oxidative Balance
  7. Telomeres in Context

Part IV — The Hormonal Systems

  1. The GLP-1 Class in Depth
  2. Next-Generation Metabolic Compounds
  3. Reading the Metabolic Panel
  4. NAD+ Precursors Examined
  5. Rapamycin and the Evidence
  6. Supplements That Earn Their Place

Part V — Hormone Optimization

  1. Testosterone: A Urologist's Framework
  2. The Growth Hormone Axis
  3. Thyroid and Metabolic Rate
  4. Menopause and Hormone Therapy
  5. DHEA and Adrenal Hormones

Part VI — Systems and Surfaces

  1. Cardiovascular Early Detection
  2. Cognitive Health and the Aging Brain
  3. Bone, Muscle, and Structural Aging
  4. Skin as an Aging Organ
  5. Sexual Wellness in Practice
  6. Aesthetic Medicine, Honestly
  7. Bladder and Pelvic Floor
  8. Sleep as Foundational Medicine

Part VII — The Integrated Practice

  1. The Integrated Framework
  2. The Comprehensive Evaluation
  3. The First 90 Days
  4. Maintenance and the Long Relationship
  5. Risk, Uncertainty, and Judgement
  6. The Limits of the Evidence
  7. The Patient as Partner
  8. What This Medicine Offers
Where to buy

Available in print and digital editions

The book is distributed through major retailers. Buy links will be listed here on publication.

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Bulk orders for practices Clinics and practices interested in bulk orders for staff or patients can contact the practice directly.
Disclosure Dr. Shusterman is the author of this book and earns royalties from its sale.

The book explains. The practice applies.

If the book’s approach resonates, a consultation is where it becomes specific to you.

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