The Science library.
Clear, evidence-rated explanations of the topics behind comprehensive longevity medicine — derived from the book, written for the web, honest about what is known.
Topic clusters
The evidence rating, explained
Every article carries an evidence rating, adapted from the framework used in the book. It tells you, at a glance, how settled the science is — from established medical knowledge down to preclinical findings that are interesting but early.
Ten articles to start with
The library grows over time. These ten cover the questions patients ask most.
What Is Comprehensive Longevity Medicine?
The paradigm explained — and clearly separated from biohacking and anti-aging marketing.
★★★★ Established Read the article › Peptides & PharmacologyPeptides Are Not Steroids: A Clear Explanation
Why the two are routinely confused, and what actually distinguishes them.
★★★★ Established Read the article › Peptides & PharmacologyTirzepatide vs. Semaglutide: How to Think About the Difference
Two GLP-1 era drugs, compared at the level of mechanism and decision-making.
★★★☆ Supported by RCT Read the article › Molecular LongevityWhat Your CAC Score Means
A coronary calcium score, explained — and how to read yours.
★★★★ Established Read the article › HormonesTestosterone Replacement: A Urologist’s Framework
How a urologist thinks about TRT — when it helps, and when it does not.
★★★☆ Supported by RCT Read the article › HormonesMenopause and Hormone Therapy in 2026
Where the evidence on menopausal hormone therapy actually stands now.
★★★☆ Supported by RCT Read the article › Molecular LongevityWhat Is NAD+ — and Does NMN Work?
A look at one of the most marketed ideas in longevity, and what the data shows.
★★☆☆ Human pilot data Read the article › Molecular LongevityRapamycin and Longevity: What the Evidence Shows
A genuinely interesting molecule — and a careful account of its evidence.
★☆☆☆ Preclinical Read the article › Molecular LongevityThe Biology of Aging, Explained
What is actually happening, at the cellular level, when we age.
★★★★ Established Read the article › Lifestyle FoundationsHow to Read Medical Evidence
The single most useful skill for navigating longevity claims.
★★★★ Established Read the article ›Begin with a consultation
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